#Source: http://biopharmnet.com/subgroup-analysis-software/												
#binary outcome	"1 for active treatment, 0 for control treatment"	Time from first sepsis-organ fail to start drug	Patient age in years	Baseline local platelets	"Sum of baselin sofa (cardiovascular, hematology, hepaticrenal, and respiration scores)"	Base creatinine	Number of baseline organ failures	Pre-infusion apache-ii score	Base GLASGOW coma scale score	Baseline serum IL-6 concentration	Baseline activity of daily living score	Baseline local bilirubin
survival	THERAPY	PRAPACHE	AGE	BLGCS	ORGANNUM	BLIL6	BLLPLAT	BLLBILI	BLLCREAT	TIMFIRST	BLADL	blSOFA
0	active	19	42.921	15	1	301.8	191	NA	1	17.17	0	5
1	active	48	68.818	11	2	118.9	NA	0.4	1.1	17.17	5	10
0	active	20	68.818	15	2	92.8	123	NA	1	10	1	7.5
0	active	19	33.174	14	2	1232	244	NA	1.2	17.17	0	6.25
0	active	48	46.532	3	4	2568	45	NA	3	10	0	12
0	control	21	56.098	14	1	162.65	137	0.5	NA	10	0	8.75
1	control	19	68.818	15	2	2568	45	NA	1	19.33	12	8.75
0	active	19	46.532	15	3	4952	92	NA	1	27.08	0	10
0	active	22	56.098	15	3	118.9	NA	2.5	5	24.5	0	12
1	active	19	56.098	10	3	2568	109	4.8	1.8	27.08	NA	12
0	control	24	59.871	15	1	301.8	650	NA	1.4	21.73	0	6.25
1	active	48	46.532	11	4	296550	45	2.5	2	34.83	NA	17
0	active	19	81.13	12	2	162.65	650	NA	1.5	30.67	3	3
1	active	29	93.336	14	2	118.9	NA	0.6	1.2	30.67	6	7.5
0	control	33	65.891	14	4	12998	284	NA	3	30.67	0	13
0	control	19	81.13	15	2	212.3	284	NA	1.5	30.67	9	12
0	control	19	76.068	15	4	92.8	650	NA	1	44.73	6	5
0	control	26	38.113	6	3	301.8	217	NA	1	39.83	0	8.75
0	active	19	81.13	15	1	92.8	153	NA	2.2	3775.9	0	6.25
0	active	25	81.13	14	3	2568	109	NA	1.8	50.67	11	13
1	active	37	68.818	10	3	519.4	359	NA	20	59.17	12	17
0	active	25	46.532	6	1	92.8	153	NA	1	67.5	0	5
1	active	19	56.098	14	2	162.65	359	NA	1.2	50.67	4	10
1	control	19	63.471	14	1	60.3	172	NA	1	67.5	0	5
0	active	19	38.113	15	3	296550	284	1.6	2.2	17.17	NA	9
1	active	19	42.921	14	1	519.4	244	0.4	1	19.33	NA	3
1	active	23	93.336	11	1	301.8	650	0.6	1.1	17.17	NA	5
0	active	37	49.823	9	2	NA	217	20.4	1.6	10	0	13
0	active	25	53.656	15	1	NA	137	20.4	1	13.78	0	6
1	control	48	81.13	5	4	NA	359	0.7	20	17.17	8	11
0	control	28	42.921	6	3	296550	92	1.4	3	17.17	NA	10
0	control	19	49.823	15	2	4952	123	0.4	1	13.78	NA	7
1	control	48	76.068	3	4	NA	284	20.4	2.4	10	0	12
0	active	20	46.532	13	4	12998	78	1.2	3	30.67	NA	12
1	active	33	65.891	7	4	723	109	1.6	3.8	24.5	NA	9
1	active	29	76.068	6	4	NA	191	0.4	1.8	21.73	0	8
0	active	26	42.921	15	2	NA	153	3.4	1.4	21.73	0	10
1	active	48	53.656	3	4	NA	78	3.4	20	21.73	0	17
1	active	48	49.823	4	5	296550	45	3.4	3.8	27.08	NA	17
1	active	27	81.13	15	4	NA	191	1.9	1	27.08	0	7
0	active	48	49.823	3	4	519.4	45	4.8	5	27.08	NA	13
0	control	27	73.138	15	2	1232	650	2.5	2.2	19.33	NA	11
0	control	22	38.113	15	1	NA	244	0.5	1	21.73	0	5
1	control	33	93.336	8	3	723	123	0.9	3	21.73	NA	11
0	active	31	76.068	14	3	92.8	78	0.4	1.4	44.73	NA	10
0	active	28	33.174	3	2	1232	92	1	1.1	44.73	NA	5
1	active	29	56.098	11	3	296550	123	0.9	20	30.67	NA	11
0	active	20	33.174	11	1	NA	153	2.5	1	30.67	0	8
0	active	27	33.174	11	1	NA	359	0.9	1	34.83	0	3
1	control	19	59.871	15	3	212.3	62	1	20	39.83	NA	10
0	active	19	49.823	15	1	118.9	650	0.5	1	67.5	NA	4
1	active	27	65.891	7	2	118.9	153	0.9	2.2	59.17	NA	6
0	active	19	73.138	15	3	37.1	109	0.5	2.4	3775.9	NA	5
0	active	25	38.113	8	3	301.8	123	0.6	5	59.17	NA	11
0	active	26	59.871	15	2	NA	172	1.2	1.5	59.17	0	9
1	active	48	68.818	3	5	12998	78	4.8	20	59.17	NA	17
1	active	26	81.13	15	3	1232	137	0.5	1.4	50.67	NA	9
0	active	20	68.818	15	2	NA	153	0.9	3.8	3775.9	0	8
0	active	19	33.174	10	1	NA	172	0.9	1	67.5	0	4
0	active	19	53.656	11	2	NA	172	1	1	50.67	0	7
0	control	31	63.471	6	4	NA	62	0.9	1.4	59.17	0	9
0	control	19	56.098	15	3	60.3	78	1.9	1.6	24.5	0	10
0	active	20	42.921	10	3	60.3	92	20.4	1.2	17.17	0	12
0	active	25	49.823	15	2	60.3	92	0.8	20	10	0	8.75
1	active	29	38.113	7	3	4952	359	1.9	1.4	19.33	12	8.75
0	active	21	49.823	15	4	406.6	78	0.6	2	13.78	3	7.5
1	active	21	93.336	15	4	12998	123	1.2	2	19.33	2	12
1	active	24	81.13	11	1	296550	359	1.2	1.6	13.78	0	4
0	active	19	46.532	13	1	212.3	92	1.9	1.1	27.08	12	6.25
0	active	19	49.823	13	1	212.3	45	0.6	1.5	27.08	0	5
1	active	19	42.921	15	1	301.8	123	1	1	21.73	0	5
1	active	29	53.656	10	2	301.8	78	4.8	2	19.33	0	10
0	active	19	33.174	15	4	2568	45	0.7	2	30.67	0	10
0	active	19	38.113	8	1	301.8	359	1.9	1	27.08	0	5
1	active	24	59.871	14	3	723	109	2.5	2	27.08	0	17
0	active	19	65.891	15	3	212.3	109	2.5	2	21.73	0	12
0	active	21	42.921	15	3	12998	62	1.2	2	19.33	0	13
0	active	28	81.13	13	2	2568	244	1.9	1	21.73	0	10
0	active	19	49.823	15	4	12998	137	0.6	2	24.5	0	8.75
0	active	19	49.823	15	1	118.9	359	0.4	1.3	24.5	0	5
0	control	33	59.871	9	1	12998	359	1.2	3	27.08	12	6.25
0	control	20	42.921	13	3	60.3	123	0.4	1.2	24.5	7	6.25
1	active	37	53.656	7	4	37.1	78	0.4	5	44.73	0	10
0	active	19	81.13	15	2	406.6	217	0.4	1.1	30.67	0	4
0	active	21	33.174	12	5	1232	78	0.4	5	44.73	0	12
1	active	19	53.656	15	3	406.6	45	20.4	1.5	39.83	0	17
1	active	19	76.068	14	1	60.3	284	20.4	1.4	34.83	4	5
0	control	33	65.891	11	3	212.3	359	3.4	2	39.83	0	13
0	control	19	42.921	15	1	92.8	650	1.4	2.4	30.67	0	4
0	control	24	76.068	13	2	2568	359	0.4	1.6	34.83	2	6.25
1	control	27	76.068	15	4	162.65	62	0.9	5	34.83	0	8.75
0	active	21	42.921	7	2	212.3	45	20.4	3.8	67.5	0	13
0	active	26	81.13	8	2	519.4	109	0.5	3.8	67.5	9	5
1	active	24	81.13	14	2	60.3	109	0.5	3.8	50.67	9	8.75
0	active	21	46.532	15	4	406.6	62	4.8	5	50.67	0	17
0	active	19	46.532	15	5	12998	62	3.4	2	59.17	0	17
0	active	19	63.471	15	1	92.8	359	0.4	1.4	50.67	0	3
1	active	31	59.871	9	3	37.1	123	20.4	2	67.5	12	10
0	active	19	42.921	15	4	118.9	78	1.4	2	59.17	0	12
0	active	19	46.532	14	1	60.3	217	1.9	1	59.17	0	6.25
1	active	19	93.336	15	2	2568	45	0.7	1.2	59.17	6	5
1	active	19	73.138	10	1	406.6	284	0.5	1	59.17	0	3
0	control	19	76.068	9	4	519.4	45	0.5	1.1	50.67	0	8.75
0	control	27	63.471	12	1	519.4	45	3.4	2.2	50.67	0	13
1	control	19	53.656	14	1	37.1	284	0.7	20	59.17	8	8.75
0	active	19	49.823	15	3	12998	359	1.9	2.2	17.17	7	9
1	active	19	73.138	14	3	4952	92	2.5	1.5	10	0	9
1	active	23	49.823	14	1	60.3	217	1.4	1	10	4	4
1	active	24	59.871	13	2	118.9	109	1.2	1.6	17.17	0	7
1	active	31	73.138	14	2	60.3	650	0.4	1.3	10	5	7
1	active	27	76.068	15	3	296550	650	0.4	1	10	3	8
1	active	28	68.818	14	3	2568	244	20.4	1	13.78	12	12
0	active	21	42.921	15	2	723	137	4.8	1.1	13.78	7	5
0	active	19	49.823	15	3	296550	78	0.5	1	13.78	11	7
0	active	19	38.113	14	1	519.4	359	4.8	1.3	10	12	7
0	active	23	46.532	15	4	296550	109	0.7	1	13.78	0	6
1	active	19	81.13	15	2	162.65	191	1.2	3	19.33	5	7
0	active	26	93.336	14	2	406.6	123	0.8	3	19.33	11	9
1	active	37	81.13	15	1	92.8	650	0.4	2.2	10	0	5
0	active	25	68.818	13	1	296550	137	0.4	1.4	13.78	9	7
1	active	31	81.13	14	2	212.3	650	0.4	1.5	10	0	7
1	active	48	53.656	12	3	212.3	92	0.6	20	13.78	12	13
0	active	22	42.921	15	3	4952	78	4.8	2.2	13.78	0	8
1	active	28	63.471	11	2	37.1	284	0.8	1	17.17	12	8
0	active	22	59.871	15	4	296550	92	1.6	1	10	9	11
1	active	19	73.138	15	1	4952	172	0.4	1.3	10	1	3
0	active	19	63.471	15	1	2568	62	0.9	1.3	17.17	0	5
1	active	37	68.818	5	3	296550	191	1.4	1.3	17.17	12	10
1	active	33	65.891	14	2	1232	244	1	1.4	10	7	8
0	active	27	42.921	6	3	296550	78	1	1	17.17	0	10
0	active	19	59.871	15	2	1232	109	20.4	1.1	10	0	9
1	active	21	81.13	12	2	723	153	0.7	1.5	13.78	0	5
1	active	19	53.656	15	1	12998	191	1.6	1.2	13.78	0	7
0	active	26	42.921	15	3	296550	137	0.7	2.4	17.17	0	11
1	active	29	93.336	9	2	212.3	359	1.2	1.1	17.17	10	6
0	active	20	46.532	8	1	37.1	284	0.7	1	13.78	0	3
0	active	19	38.113	15	3	296550	172	0.6	2	10	0	7
1	active	33	73.138	13	3	12998	123	1.9	2.4	10	5	12
1	active	48	81.13	10	3	12998	244	2.5	2.2	19.33	6	11
0	active	24	63.471	15	2	60.3	650	0.8	1.1	10	2	3
1	active	37	81.13	4	3	296550	109	0.8	3	13.78	0	10
1	active	33	38.113	14	1	60.3	217	0.7	20	10	0	6
1	active	19	46.532	15	1	37.1	172	0.6	1	10	0	3
0	active	26	65.891	12	2	37.1	217	3.4	2.2	17.17	0	11
0	active	19	33.174	11	3	212.3	45	20.4	3	13.78	12	11
0	active	21	81.13	15	2	12998	191	1	1.2	17.17	1	7
1	active	28	65.891	6	4	2568	217	1.6	3.8	10	0	10
0	active	19	56.098	15	3	92.8	191	0.5	1.2	17.17	0	8
0	active	20	33.174	15	3	12998	191	4.8	1.5	17.17	9	10
1	active	28	53.656	14	1	1232	650	0.4	1	10	8	3
0	active	19	73.138	15	1	1232	191	1.9	2.2	10	0	7
0	active	19	53.656	15	1	60.3	172	1.6	1	10	7	5
0	active	19	68.818	15	2	12998	191	0.4	1	13.78	0	5
0	active	19	93.336	15	1	519.4	137	20.4	1.6	10	0	7
1	active	37	63.471	15	1	519.4	359	0.5	20	19.33	0	10
1	active	22	65.891	14	2	162.65	650	3.4	1.8	13.78	0	10
1	active	37	63.471	4	1	37.1	650	0.5	1	13.78	12	6
1	active	37	73.138	9	3	4952	217	0.8	2.2	17.17	2	10
0	active	33	33.174	3	1	60.3	123	0.9	1	10	0	6
0	active	23	81.13	12	4	1232	123	0.9	1	17.17	9	8
1	active	22	49.823	7	1	723	244	2.5	1.2	13.78	0	7
0	active	20	46.532	15	2	1232	244	0.9	1.2	13.78	0	9
0	active	48	76.068	10	3	406.6	191	3.4	3	13.78	0	7
1	active	31	76.068	6	2	212.3	62	20.4	3	17.17	12	11
1	active	29	76.068	8	3	406.6	92	1	1.4	13.78	0	9
0	active	19	59.871	15	1	92.8	244	1	1	13.78	0	4
0	active	27	38.113	15	1	12998	153	0.9	2.4	13.78	0	10
1	control	20	53.656	14	1	37.1	172	0.6	2.2	13.78	0	7
1	control	21	33.174	15	2	162.65	62	1.9	1	13.78	0	6
1	control	23	49.823	11	2	2568	153	0.7	1	10	0	7
1	control	19	49.823	15	2	723	45	3.4	1	10	0	10
0	control	19	49.823	15	2	12998	244	0.8	1.4	13.78	0	5
0	control	20	93.336	15	2	92.8	284	0.6	1	17.17	2	6
1	control	33	59.871	9	2	723	284	0.4	1	17.17	0	7
0	control	19	73.138	15	1	1232	217	0.9	1.3	17.17	0	7
1	control	27	59.871	15	2	4952	109	1	3.8	19.33	0	10
0	control	48	65.891	12	3	296550	217	4.8	1.6	13.78	5	11
0	control	21	56.098	14	1	162.65	109	3.4	2.4	10	0	9
0	control	29	53.656	13	4	162.65	359	0.6	3.8	13.78	0	10
0	control	37	93.336	11	3	296550	217	0.6	3	10	0	10
0	control	28	68.818	14	3	12998	284	0.4	1	17.17	1	8
0	control	28	73.138	15	2	118.9	123	20.4	1	19.33	0	9
1	control	19	93.336	14	2	4952	217	1	1	10	0	4
0	control	23	38.113	15	3	92.8	123	0.6	3.8	17.17	0	6
1	control	19	73.138	15	2	212.3	244	0.4	1.4	10	10	5
1	control	48	42.921	13	4	296550	284	0.6	3.8	17.17	0	9
0	control	19	49.823	11	4	406.6	217	1.2	1	19.33	0	4
0	control	23	42.921	15	4	2568	45	1.9	1.1	10	0	10
0	control	29	68.818	7	3	296550	123	0.7	1	13.78	7	9
0	control	19	46.532	15	1	162.65	650	0.6	1.1	10	0	3
1	control	21	63.471	15	1	519.4	284	1.4	1.6	17.17	0	5
0	control	21	68.818	15	2	723	217	1.9	3	17.17	0	10
0	control	20	38.113	13	2	12998	191	0.4	1.8	10	0	8
1	active	33	63.471	11	3	4952	109	2.5	1.8	19.33	1	11
1	active	33	76.068	13	4	37.1	78	0.5	3	21.73	8	10
1	active	29	73.138	10	2	301.8	191	1.2	1	27.08	0	8
1	active	24	68.818	14	3	2568	123	4.8	1	19.33	0	8
1	active	23	81.13	14	3	4952	172	0.9	3.8	27.08	0	11
0	active	22	65.891	14	2	92.8	137	0.4	1.8	21.73	3	9
0	active	22	33.174	15	4	296550	153	3.4	3	24.5	0	12
0	active	22	53.656	15	3	2568	45	1.4	2.4	24.5	0	13
1	active	28	81.13	15	1	212.3	123	0.4	20	21.73	0	7
0	active	21	73.138	15	3	4952	137	1.9	2.2	21.73	0	6
0	active	28	59.871	15	4	37.1	191	1.4	1	24.5	1	8
0	active	19	76.068	12	3	162.65	62	1.6	1.8	24.5	1	6
1	active	48	81.13	9	3	162.65	153	0.4	2.4	27.08	0	10
1	active	25	76.068	10	2	212.3	217	0.4	1.3	24.5	10	8
0	active	20	38.113	12	1	723	109	1.9	1.2	19.33	0	7
1	active	19	59.871	12	1	1232	109	0.5	1.2	27.08	0	6
0	active	31	46.532	3	4	406.6	359	0.7	1.1	19.33	7	7
1	active	33	73.138	12	1	723	191	20.4	2.4	19.33	0	8
1	active	31	93.336	15	4	301.8	92	0.5	3	21.73	9	7
1	active	37	68.818	8	3	12998	78	3.4	1.5	27.08	0	11
1	active	48	76.068	3	2	296550	284	0.9	3	24.5	11	9
0	active	22	76.068	15	1	37.1	244	0.4	1.8	19.33	0	6
0	active	20	56.098	14	5	212.3	92	1.6	5	21.73	0	10
1	active	37	73.138	9	3	1232	244	1.4	1.8	24.5	8	10
0	active	24	59.871	14	2	519.4	137	0.7	20	24.5	0	11
0	active	22	42.921	15	2	1232	244	0.8	3	21.73	0	10
1	active	19	53.656	10	1	92.8	217	1.2	1.3	21.73	0	3
0	active	26	65.891	9	2	37.1	137	1.6	1	24.5	0	7
0	active	33	49.823	11	2	212.3	123	0.7	20	24.5	5	12
1	active	37	53.656	3	2	118.9	172	0.7	20	21.73	1	11
1	active	19	81.13	15	1	519.4	244	0.4	1.4	27.08	0	6
1	active	27	68.818	15	2	60.3	650	0.8	1.4	21.73	0	6
0	active	26	56.098	11	5	296550	78	3.4	1.4	27.08	9	12
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0	control	25	49.823	12	5	60.3	78	4.8	5	67.5	0	17
0	control	28	46.532	9	2	406.6	123	1.9	1	3775.9	0	9
0	control	19	59.871	7	2	92.8	78	0.7	1	3775.9	0	3
0	control	25	65.891	15	4	2568	62	1.2	3.8	50.67	0	9
0	control	19	33.174	15	1	1232	62	0.8	1.2	67.5	0	3
0	control	19	59.871	15	3	118.9	92	20.4	20	67.5	0	12
0	control	19	49.823	15	4	2568	45	3.4	5	3775.9	8	17
0	control	33	56.098	3	3	2568	284	2.5	1	59.17	0	9
0	control	26	46.532	4	2	212.3	45	2.5	1.2	67.5	0	10
0	control	37	93.336	5	2	212.3	217	0.4	3.8	3775.9	8	6
0	control	22	68.818	6	3	723	78	4.8	1	3775.9	0	11
0	control	27	53.656	15	2	301.8	359	0.7	1.2	67.5	0	9
0	control	19	65.891	15	3	37.1	359	0.4	3.8	67.5	0	8
1	control	25	33.174	3	1	212.3	137	0.4	1	3775.9	0	7
0	control	19	59.871	14	1	37.1	650	4.8	1	3775.9	11	5
0	control	19	38.113	10	1	37.1	191	0.5	1	59.17	0	3
0	control	37	73.138	3	2	92.8	153	2.5	1	50.67	0	9